Scientific publications by Prof. Dr. Mehmet Çolakoğlu

Annals of Clinical and Analytical Medicine

The association of ovarian hyperstimulation syndrome in the early ovulation induction and procalcitonin in patients with polycystic ovary syndrome

Author / Co-authorProf. Dr. Mehmet Cengiz Çolakoğlu

Journal publication

Brief summary: In 60 patients with and without PCOS, the study examined procalcitonin and ovarian hyperstimulation syndrome. A day-five increase in those developing OHSS suggested a possible early marker, rather than an established standalone diagnostic test.

Česká gynekologie

Can anti-Müllerian hormone predict positive sperm retrieval in men with idiopathic non-obstructive azoospermia?

Author / Co-authorProf. Dr. Mehmet Cengiz Çolakoğlu

Çolakoğlu MC, Horasanlı JE, Tül M, Gencel B, Akkuş F.

Journal publication

Brief summary: This retrospective study of 72 men with idiopathic non-obstructive azoospermia examined AMH as a predictor of sperm retrieval with micro-TESE. Higher AMH was associated with unsuccessful retrieval; the findings cannot guarantee an individual outcome.

DOI: 10.48095/cccg2025285

Ege Tıp Dergisi

Effectiveness of foley catheter usage time in prevention of urinary fistula in laparoscopic hysterectomy

Author / Co-authorProf. Dr. Mehmet Cengiz Çolakoğlu

Journal publication

Brief summary: Records from 312 laparoscopic hysterectomies were reviewed for catheter duration and urinary fistula. Longer Foley use was associated with lower fistula risk; the observational design does not establish one catheter schedule for every patient.

Annals of Clinical and Analytical Medicine

Investigation of the effect of FSH/LH ratio on pregnancy success before IVF in infertile patients

Author / Co-authorProf. Dr. Mehmet Cengiz Çolakoğlu

Journal publication

Brief summary: In 265 IVF patients, baseline FSH/LH ratio was examined against ovarian response and pregnancy outcomes. A higher ratio was associated with a lower egg response, without a significant difference in pregnancy or live birth rates.

Mersin Üniversitesi Sağlık Bilimleri Dergisi

Agonist/antagonist kontrollü over hiperstimülasyon rejimlerinde serum ve folliküler sıvı iskemi modifiye albümin düzeyleri ve gebelik oranları ile ilişkisi

Author / Co-authorProf. Dr. Mehmet Cengiz Çolakoğlu

Journal publication

Brief summary: Sixty normal responders were compared across agonist and antagonist IVF protocols using serum and follicular-fluid ischaemia-modified albumin. Clinical pregnancy rates were similar; the oxidative-stress marker findings should be interpreted within their research setting.

Annals of Clinical and Analytical Medicine

Investigation of peripheral natural killer cell activity in recurrent miscarriages of unknown cause

Author / Co-authorProf. Dr. Mehmet Cengiz Çolakoğlu

Journal publication

Brief summary: The study investigates peripheral natural killer cell activity in unexplained recurrent miscarriage. It explores a possible immune association with pregnancy loss and should not be read as a recommendation for routine NK testing or immune treatment.

International Journal of Diabetes in Developing Countries

Role of ChREBP and SREBP-1c in gestational diabetes: two key players in glucose and lipid metabolism

Author / Co-authorProf. Dr. Mehmet Cengiz Çolakoğlu

Journal publication

Brief summary: ChREBP and SREBP-1c levels were compared in 50 pregnancies with gestational diabetes and 52 with normal glucose tolerance. Lower levels were found in the diabetes group, exploring biological pathways linking glucose and lipid metabolism.

Harran Üniversitesi Tıp Fakültesi Dergisi

Erken Gebelikte Kullanılan Vajinal, İntramuskuler veya Kombine Progesteronun Serum Progesteron Düzeylerine Etkisinin Karşılaştırılması

Author / Co-authorProf. Dr. Mehmet Cengiz Çolakoğlu

Journal publication

Brief summary: Among 64 women receiving progesterone for threatened miscarriage, vaginal, intramuscular and combined administration were compared. Combined treatment raised serum progesterone faster; this does not by itself demonstrate a higher live birth rate.

Turkish Journal of Obstetrics and Gynecology

Endometrial CD56+ natural killer cells in women with recurrent implantation failure: An immunohistochemical study

Author / Co-authorProf. Dr. Mehmet Cengiz Çolakoğlu

Babayeva G, Purut YE, Giray B, Oltulu P, Alakuş R, Çolakoğlu MC.

Journal publication

Brief summary: Endometrial CD56+ NK cells were compared in 25 women with recurrent implantation failure and 25 with previous live birth. Lower counts were found in the failure group; this small study did not test treatment effectiveness.

DOI: 10.4274/tjod.galenos.2020.90359

Selçuk Tıp Dergisi

IVF Sonrası Canlı Doğumla Sonuçlanan Heterotopik Gebelik; Olgu Sunumu

Author / Co-authorProf. Dr. Mehmet Cengiz Çolakoğlu

Journal publication

Brief summary: This case report describes simultaneous intrauterine and ectopic pregnancy after IVF. Following surgery for the ectopic pregnancy, the intrauterine pregnancy reached term; a single case does not establish a general success rate.

Şişli Etfal Hastanesi Tıp Bülteni

Genetik amniyosentez sonuçlarımız: 3721 vakanın analizi

Author / Co-authorProf. Dr. Mehmet Cengiz Çolakoğlu

Journal publication

Brief summary: This retrospective series reviews seven years of genetic amniocentesis, including indications and detected chromosome abnormalities. It contributes clinical data relevant to prenatal diagnosis and genetic counselling.

Gynecological Endocrinology

The evaluation of recombinant LH supplementation in patients with suboptimal response to recombinant FSH undergoing IVF treatment with GnRH agonist down-regulation

Author / Co-authorProf. Dr. Mehmet Cengiz Çolakoğlu

Yazıcı Yılmaz F, Görkemli H, Çolakoğlu MC, Aktan M, Gezginç K.

Journal publication

Brief summary: In suboptimal IVF responders, recombinant LH supplementation was compared with increasing FSH. Results favoured LH in the selected group; they do not establish that every patient benefits from routine LH supplementation.

DOI: 10.3109/09513590.2014.965675

Journal of Obstetrics and Gynaecology

Expression of cyclin A, cyclin E and p27 in normal, hyperplastic and frankly malignant endometrial samples

Author / Co-authorProf. Dr. Mehmet Cengiz Çolakoğlu

Gezginc ST, Celik C, Dogan NU, Toy H, Tazegul A, Colakoglu MC.

Journal publication

Brief summary: Cyclin A, cyclin E and p27 staining was studied in 75 normal, hyperplastic and malignant endometrial samples. Increased cyclin E and reduced p27 in cancer samples contributed to research into cell-cycle regulation.

DOI: 10.3109/01443615.2013.776024

Journal of Obstetrics and Gynaecology

Removal of intra-abdominal mislocated intrauterine devices by laparoscopy

Author / Co-authorProf. Dr. Mehmet Cengiz Çolakoğlu

Balci O, Capar M, Mahmoud AS, Colakoglu MC.

Journal publication

Brief summary: Fifteen patients undergoing laparoscopic removal of intra-abdominally displaced IUDs were reviewed retrospectively. The series describes device locations and surgical outcomes; removal decisions require individual risk assessment.

DOI: 10.3109/01443615.2011.593646

Journal of Obstetrics and Gynaecology Research

Effect of pre-amniocentesis counseling on maternal pain and anxiety

Author / Co-authorProf. Dr. Mehmet Cengiz Çolakoğlu

Balci O, Acar A, Mahmoud AS, Colakoglu MC.

Journal publication

Brief summary: In 240 pregnancies, counselling before amniocentesis was evaluated for anticipated and experienced pain and anxiety. The findings support the value of clear information in the procedure experience.

DOI: 10.1111/j.1447-0756.2011.01621.x

Journal of Obstetrics and Gynaecology Research

Balci technique for suspending vaginal vault at vaginal hysterectomy with reduced risk of vaginal vault prolapse

Author / Co-authorProf. Dr. Mehmet Cengiz Çolakoğlu

Balci O, Capar M, Acar A, Colakoglu MC.

Journal publication

Brief summary: A new vaginal vault suspension technique at vaginal hysterectomy was compared with the conventional approach. Four-year follow-up reported less vault prolapse and greater vaginal length with the new technique.

DOI: 10.1111/j.1447-0756.2010.01430.x

Archives of Gynecology and Obstetrics

Management and outcomes of adnexal torsion: a 5-year experience

Author / Co-authorProf. Dr. Mehmet Cengiz Çolakoğlu

Balci O, Icen MS, Mahmoud AS, Capar M, Colakoglu MC.

Journal publication

Brief summary: Surgical outcomes in 150 patients treated for adnexal torsion over five years were reviewed. Age, fertility preservation and suspicion of malignancy were discussed as important factors in selecting a surgical approach.

DOI: 10.1007/s00404-010-1702-z

The Journal of Maternal-Fetal & Neonatal Medicine

Comparison of induction of labor with vaginal misoprostol plus oxytocin versus oxytocin alone in term primigravidae

Author / Co-authorProf. Dr. Mehmet Cengiz Çolakoğlu

Balci O, Mahmoud AS, Acar A, Colakoglu MC.

Journal publication

Brief summary: In 101 first pregnancies, misoprostol followed by oxytocin was compared with oxytocin alone for labour induction. The combined approach shortened time to delivery; drug selection and safety require obstetric assessment.

DOI: 10.3109/14767058.2010.531798

Gynecologic and Obstetric Investigation

The effect of antenatal steroids on fetal lung maturation between the 34th and 36th week of pregnancy

Author / Co-authorProf. Dr. Mehmet Cengiz Çolakoğlu

Balci O, Ozdemir S, Mahmoud AS, Acar A, Colakoglu MC.

Journal publication

Brief summary: Antenatal betamethasone was evaluated in 100 pregnancies at risk of delivery at 34–36 weeks. Fewer newborn respiratory problems occurred in the steroid group; the authors called for larger studies.

DOI: 10.1159/000295898

Fertility and Sterility

The efficacy of multiple-dose methotrexate treatment for unruptured tubal ectopic pregnancy and conversion rate to surgery: a study on 294 cases

Author / Co-authorProf. Dr. Mehmet Cengiz Çolakoğlu

Balci O, Ozdemir S, Mahmoud AS, Acar A, Colakoglu MC.

Journal publication

Brief summary: Multiple-dose methotrexate and conversion to surgery were studied in 294 unruptured tubal ectopic pregnancies. Outcome was more closely related to mass size than initial beta-hCG; this historical series is not a current treatment protocol.

DOI: 10.1016/j.fertnstert.2009.09.014

Gynecologic and Obstetric Investigation

Comparison of modified biophysical profile and Doppler ultrasound in predicting the perinatal outcome at or over 36 weeks of gestation

Author / Co-authorProf. Dr. Mehmet Cengiz Çolakoğlu

Bardakci M, Balci O, Acar A, Colakoglu MC.

Journal publication

Brief summary: Modified biophysical profile and Doppler ultrasound were compared in 315 pregnancies at or beyond 36 weeks. Combining the assessments increased sensitivity for predicting certain perinatal outcomes.

DOI: 10.1159/000274488

Taiwanese Journal of Obstetrics and Gynecology

Management of ovarian cysts by laparoscopic extracorporeal approach using single ancillary trocar

Author / Co-authorProf. Dr. Mehmet Cengiz Çolakoğlu

Capar M, Balci O, Acar A, Colakoglu MC.

Journal publication

Brief summary: A laparoscopic extracorporeal approach using one ancillary trocar was assessed in 220 selected patients with presumed benign ovarian cysts. Operating time, cyst removal and complications were reviewed to evaluate feasibility.

DOI: 10.1016/s1028-4559(09)60327-2

Acta Obstetricia et Gynecologica Scandinavica

Does tenaculum application to the cervix during intrauterine insemination affect pregnancy rates?

Author / Co-authorProf. Dr. Mehmet Cengiz Çolakoğlu

Balci O, Acar A, Colakoglu MC.

Journal publication

Brief summary: In 468 patients, cervical tenaculum application during IUI was examined for uterine contractions and pregnancy outcomes. More contractions and higher pregnancy rates were reported in the application group; one study does not establish routine necessity.

DOI: 10.1080/00016340903118000

Gynecologic and Obstetric Investigation

Repeated in vitro fertilization failure and its relation with thrombophilia

Author / Co-authorProf. Dr. Mehmet Cengiz Çolakoğlu

Simur A, Ozdemir S, Acar H, Colakoğlu MC, Görkemli H, Balci O, Nergis S.

Journal publication

Brief summary: Selected inherited thrombophilia variants were compared between women with repeated IVF failure and controls. The study found no significant association between the tested mutations and implantation failure.

DOI: 10.1159/000165776

Journal of Obstetrics and Gynaecology Research

Management and outcomes of adnexal masses during pregnancy: A 6-year experience

Author / Co-authorProf. Dr. Mehmet Cengiz Çolakoğlu

Balci O, Gezginc K, Karatayli R, Acar A, Celik C, Colakoglu MC.

Journal publication

Brief summary: A six-year series reviewed adnexal masses requiring surgery during pregnancy. Most were benign; the results reflect a selected population at a tertiary referral centre.

DOI: 10.1111/j.1447-0756.2008.00744.x

Taiwanese Journal of Obstetrics and Gynecology

Comparison of single versus double intrauterine insemination

Author / Co-authorProf. Dr. Mehmet Cengiz Çolakoğlu

Gezginç K, Görkemli H, Celik C, Karatayli R, Ciçek MN, Olakoglu MC.

Journal publication

Brief summary: Single and double IUI were compared in a randomised study of 100 infertile patients. Pregnancy rates did not differ significantly; the authors noted the need for larger studies.

DOI: 10.1016/s1028-4559(08)60055-8

BJOG

The treatment of 65 women with imperforate hymen by a central incision and application of Foley catheter

Author / Co-authorProf. Dr. Mehmet Cengiz Çolakoğlu

Acar A, Balci O, Karatayli R, Capar M, Colakoglu MC.

Journal publication

Brief summary: Outcomes of central incision with Foley catheter placement were reported in 65 patients treated for imperforate hymen. The study evaluates patency of the opening and the surgical approach.

DOI: 10.1111/j.1471-0528.2007.01446.x

The European Journal of Contraception & Reproductive Health Care

Contraceptive efficacy and side effects of Implanon

Author / Co-authorProf. Dr. Mehmet Cengiz Çolakoğlu

Gezginc K, Balci O, Karatayli R, Colakoglu MC.

Journal publication

Brief summary: Efficacy, side effects and reasons for removal were followed in 80 Implanon users. Changes in bleeding patterns were highlighted as an important part of counselling before insertion.

DOI: 10.1080/13625180701548040

Geburtshilfe und Frauenheilkunde

Comparison of tubal transfer and transcervical uterine embryo transfer of immediate injected oocytes and 2–3 days old cultured embryos

Author / Co-authorProf. Dr. Mehmet Cengiz Çolakoğlu

Journal publication

Brief summary: Rapid tubal transfer after ICSI was compared with uterine embryo transfer. No improvement was demonstrated; laparoscopy and multiple-pregnancy risks led the authors to question its clinical suitability.

Archives of Gynecology and Obstetrics

Serum TNF-alpha, IL-6, lupus anticoagulant and anticardiolipin antibody in women with and without a past history of recurrent miscarriage

Author / Co-authorProf. Dr. Mehmet Cengiz Çolakoğlu

Arslan E, Colakoğlu M, Celik C, Gezginç K, Acar A, Capar M, Aköz M, Akyürek C.

Journal publication

Brief summary: TNF-alpha, IL-6 and antiphospholipid markers were compared in women with and without recurrent miscarriage. An association with TNF-alpha was reported, without establishing causality or treatment effectiveness.

DOI: 10.1007/s00404-003-0547-0

International Urogynecology Journal and Pelvic Floor Dysfunction

A new needle suspension procedure for genuine stress incontinence and anterior vaginal wall prolapse

Author / Co-authorProf. Dr. Mehmet Cengiz Çolakoğlu

Colakoğlu M, Capar M, Kiliç M, Colakoğlu U, Kaya H, Acar A.

Journal publication

Brief summary: A new suspension procedure for stress urinary incontinence and anterior vaginal wall prolapse is described through experience in 31 patients. It aims to support the bladder neck and vaginal wall.

DOI: 10.1007/bf01902374

The American Journal of Medicine

Commencement of normal menstrual cycles after 17 years in a patient with Sheehan’s syndrome

Author / Co-authorProf. Dr. Mehmet Cengiz Çolakoğlu

Colakoğlu M, Erçal T, Karslioğlu S.

Journal publication

Brief summary: This case report concerns the return of normal menstrual cycles after 17 years in a patient with Sheehan’s syndrome. As the index record has no abstract, this description is limited to the subject stated in the title.

DOI: 10.1016/0002-9343(87)90480-3

Clinical and Experimental Obstetrics & Gynecology

The effect of dehydroepiandrosterone sulfate prolactin and testosterone hormones in female fertility and hirsutism

Author / Co-authorProf. Dr. Mehmet Cengiz Çolakoğlu

Colakoglu M.

Journal publication

Brief summary: The study investigated DHEAS, prolactin and testosterone in female infertility and hirsutism. Its historical hormone findings should not be used as current diagnostic thresholds or individual treatment advice.