Male infertility and sperm selection · 2026

Advanced sperm selection: updated Cochrane evidence

Systematic review / meta-analysis · 3752 women

Library updated:

Advanced sperm selection: updated Cochrane evidence

What was investigated and what was found?

Live-birth benefits remained uncertain across several advanced selection methods. Hyaluronic-acid selection may reduce miscarriage, but this does not establish equivalent benefits for all techniques.

Interpreting the findings

Patient groups, methods and bias risks can differ across studies. A pooled estimate is not a personal treatment recommendation or a guarantee of benefit.

How can you prepare for a consultation?

Bring semen analyses, any DNA-fragmentation or urology/andrology reports, and previous fertilization results. Findings from both partners should guide discussion of IVF or ICSI planning.

What does this research mean for your situation?

Let us begin with your diagnosis, previous findings and goals as a couple. You can request an initial consultation with Prof. Dr. Mehmet Çolakoğlu to discuss what this research means for your own situation.

Request an initial consultation

Return to the research library

The first step towards your dream of a child

Consultation and Contact Form

Use this form to request an appointment, arrange an initial consultation or ask a general question. Prof. Dr. Mehmet Çolakoğlu’s team will contact you.

Prof. Dr. Mehmet Çolakoğlu
A newborn grasping a mother’s finger with both parents’ hands supporting gently
Let us get to know you

Please do not include identity numbers, medical reports or documents. You can discuss details during your consultation.

WhatsApp