
The IVF Process and Success
What Are PRP and Exosomes in IVF Treatment?
Understand ovarian and intrauterine PRP, how exosomes differ, the limits of fertility research, possible risks and questions to discuss at your consultation.
Read the articleProf. Dr. Mehmet Çolakoğlu
Explore your questions at your own pace. Guides, video explanations, social media posts and scientific research, all in one place.
Treatment stages, cost planning and frequently asked questions.
IVF and reproductive health explained by your doctor.
Health insights and stories that began with the dream of a child.
Research and publications co-authored by Prof. Dr. Mehmet Çolakoğlu.
Causes, assessments and first steps for women and men.
01 · 15
Treatment stages, cost planning and frequently asked questions.

The IVF Process and Success
Understand ovarian and intrauterine PRP, how exosomes differ, the limits of fertility research, possible risks and questions to discuss at your consultation.
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IVF Prices and Costs
Understand how IVF costs are determined after assessment, what to ask about medicines and procedures, and how to prepare a personal treatment budget.
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IVF Prices and Costs
Researching IVF costs in Konya? Prepare questions about consultations, necessary tests, medicines, treatment locations and your individual budget.
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IVF Prices and Costs
Explore questions about IVF costs in Ankara, a consultation in Etimesgut, necessary investigations, hospital services and your treatment budget.
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IVF Prices and Costs
Planning IVF from Karaman? Consider personal treatment costs, consultations in Konya or Ankara, follow-up arrangements and your travel budget.
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The IVF Process and Success
Can IVF succeed the first time? Understand a first transfer versus a treatment cycle, individual expectations and options after an unsuccessful result.
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The IVF Process and Success
Explore decisions after unsuccessful IVF: reviewing previous records, timing another attempt, necessary investigations and your personal priorities.
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The IVF Process and Success
Understanding IVF helps you make informed decisions. The process involves much more than injections or embryo transfer: it starts with assessing both partners and agreeing on a personal plan.
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The IVF Process and Success
IVF may be an option, but the first question is why it is appropriate for you. A single hormone value or an online success percentage cannot answer that question.
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The IVF Process and Success
Good preparation is not about buying every available test. It means collecting useful health information, completing appropriate checks and building a treatment plan that fits everyday life.
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The IVF Process and Success
Small practical details can become major concerns in a first cycle. Your medicines and dates are individual; these questions help you obtain clear instructions from your own team.
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The IVF Process and Success
Names such as time-lapse, ERA, PRP and genetic screening appear frequently in fertility discussions. A newer procedure does not necessarily increase the chance of live birth for every patient.
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The IVF Process and Success
Artificial intelligence is increasingly discussed in IVF laboratories. Classifying images accurately, however, is not the same as showing that a couple will have a baby.
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The IVF Process and Success
Freezing embryos can make treatment timing more flexible. Choosing a fresh or frozen transfer nevertheless requires an individual decision rather than one answer for every patient.
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The IVF Process and Success
Fertility assessment concerns both partners. Exploring male factors early can save time and make it clearer why a particular treatment is being recommended.
Read the article02 · 28
IVF and reproductive health explained by your doctor.
FROM THE ARCHIVE · December 8, 2020
FROM THE ARCHIVE · February 6, 2015
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04 · 34
Research and publications co-authored by Prof. Dr. Mehmet Çolakoğlu.

Annals of Clinical and Analytical Medicine
Journal publication
Brief summary: In 60 patients with and without PCOS, the study examined procalcitonin and ovarian hyperstimulation syndrome. A day-five increase in those developing OHSS suggested a possible early marker, rather than an established standalone diagnostic test.
Open article / publication record
Česká gynekologie
Journal publication
Brief summary: This retrospective study of 72 men with idiopathic non-obstructive azoospermia examined AMH as a predictor of sperm retrieval with micro-TESE. Higher AMH was associated with unsuccessful retrieval; the findings cannot guarantee an individual outcome.
Open article / publication recordDOI: 10.48095/cccg2025285

Ege Tıp Dergisi
Journal publication
Brief summary: Records from 312 laparoscopic hysterectomies were reviewed for catheter duration and urinary fistula. Longer Foley use was associated with lower fistula risk; the observational design does not establish one catheter schedule for every patient.
Open article / publication record
Annals of Clinical and Analytical Medicine
Journal publication
Brief summary: In 265 IVF patients, baseline FSH/LH ratio was examined against ovarian response and pregnancy outcomes. A higher ratio was associated with a lower egg response, without a significant difference in pregnancy or live birth rates.
Open article / publication record
Mersin Üniversitesi Sağlık Bilimleri Dergisi
Journal publication
Brief summary: Sixty normal responders were compared across agonist and antagonist IVF protocols using serum and follicular-fluid ischaemia-modified albumin. Clinical pregnancy rates were similar; the oxidative-stress marker findings should be interpreted within their research setting.
Open article / publication record
Annals of Clinical and Analytical Medicine
Journal publication
Brief summary: The study investigates peripheral natural killer cell activity in unexplained recurrent miscarriage. It explores a possible immune association with pregnancy loss and should not be read as a recommendation for routine NK testing or immune treatment.
Open article / publication record
International Journal of Diabetes in Developing Countries
Journal publication
Brief summary: ChREBP and SREBP-1c levels were compared in 50 pregnancies with gestational diabetes and 52 with normal glucose tolerance. Lower levels were found in the diabetes group, exploring biological pathways linking glucose and lipid metabolism.
Open article / publication record
Harran Üniversitesi Tıp Fakültesi Dergisi
Journal publication
Brief summary: Among 64 women receiving progesterone for threatened miscarriage, vaginal, intramuscular and combined administration were compared. Combined treatment raised serum progesterone faster; this does not by itself demonstrate a higher live birth rate.
Open article / publication record
Turkish Journal of Obstetrics and Gynecology
Journal publication
Brief summary: Endometrial CD56+ NK cells were compared in 25 women with recurrent implantation failure and 25 with previous live birth. Lower counts were found in the failure group; this small study did not test treatment effectiveness.
Open article / publication recordDOI: 10.4274/tjod.galenos.2020.90359

Selçuk Tıp Dergisi
Journal publication
Brief summary: This case report describes simultaneous intrauterine and ectopic pregnancy after IVF. Following surgery for the ectopic pregnancy, the intrauterine pregnancy reached term; a single case does not establish a general success rate.
Open article / publication record
Şişli Etfal Hastanesi Tıp Bülteni
Journal publication
Brief summary: This retrospective series reviews seven years of genetic amniocentesis, including indications and detected chromosome abnormalities. It contributes clinical data relevant to prenatal diagnosis and genetic counselling.
Open article / publication record
Gynecological Endocrinology
Journal publication
Brief summary: In suboptimal IVF responders, recombinant LH supplementation was compared with increasing FSH. Results favoured LH in the selected group; they do not establish that every patient benefits from routine LH supplementation.
Open article / publication recordDOI: 10.3109/09513590.2014.965675

Journal of Obstetrics and Gynaecology
Journal publication
Brief summary: Cyclin A, cyclin E and p27 staining was studied in 75 normal, hyperplastic and malignant endometrial samples. Increased cyclin E and reduced p27 in cancer samples contributed to research into cell-cycle regulation.
Open article / publication recordDOI: 10.3109/01443615.2013.776024

Journal of Obstetrics and Gynaecology
Journal publication
Brief summary: Fifteen patients undergoing laparoscopic removal of intra-abdominally displaced IUDs were reviewed retrospectively. The series describes device locations and surgical outcomes; removal decisions require individual risk assessment.
Open article / publication recordDOI: 10.3109/01443615.2011.593646

Journal of Obstetrics and Gynaecology Research
Journal publication
Brief summary: In 240 pregnancies, counselling before amniocentesis was evaluated for anticipated and experienced pain and anxiety. The findings support the value of clear information in the procedure experience.
Open article / publication recordDOI: 10.1111/j.1447-0756.2011.01621.x

Journal of Obstetrics and Gynaecology Research
Journal publication
Brief summary: A new vaginal vault suspension technique at vaginal hysterectomy was compared with the conventional approach. Four-year follow-up reported less vault prolapse and greater vaginal length with the new technique.
Open article / publication recordDOI: 10.1111/j.1447-0756.2010.01430.x

Archives of Gynecology and Obstetrics
Journal publication
Brief summary: Surgical outcomes in 150 patients treated for adnexal torsion over five years were reviewed. Age, fertility preservation and suspicion of malignancy were discussed as important factors in selecting a surgical approach.
Open article / publication recordDOI: 10.1007/s00404-010-1702-z

The Journal of Maternal-Fetal & Neonatal Medicine
Journal publication
Brief summary: In 101 first pregnancies, misoprostol followed by oxytocin was compared with oxytocin alone for labour induction. The combined approach shortened time to delivery; drug selection and safety require obstetric assessment.
Open article / publication recordDOI: 10.3109/14767058.2010.531798

Gynecologic and Obstetric Investigation
Journal publication
Brief summary: Antenatal betamethasone was evaluated in 100 pregnancies at risk of delivery at 34–36 weeks. Fewer newborn respiratory problems occurred in the steroid group; the authors called for larger studies.
Open article / publication recordDOI: 10.1159/000295898

Fertility and Sterility
Journal publication
Brief summary: Multiple-dose methotrexate and conversion to surgery were studied in 294 unruptured tubal ectopic pregnancies. Outcome was more closely related to mass size than initial beta-hCG; this historical series is not a current treatment protocol.
Open article / publication recordDOI: 10.1016/j.fertnstert.2009.09.014

Gynecologic and Obstetric Investigation
Journal publication
Brief summary: Modified biophysical profile and Doppler ultrasound were compared in 315 pregnancies at or beyond 36 weeks. Combining the assessments increased sensitivity for predicting certain perinatal outcomes.
Open article / publication recordDOI: 10.1159/000274488

Taiwanese Journal of Obstetrics and Gynecology
Journal publication
Brief summary: A laparoscopic extracorporeal approach using one ancillary trocar was assessed in 220 selected patients with presumed benign ovarian cysts. Operating time, cyst removal and complications were reviewed to evaluate feasibility.
Open article / publication recordDOI: 10.1016/s1028-4559(09)60327-2

Acta Obstetricia et Gynecologica Scandinavica
Journal publication
Brief summary: In 468 patients, cervical tenaculum application during IUI was examined for uterine contractions and pregnancy outcomes. More contractions and higher pregnancy rates were reported in the application group; one study does not establish routine necessity.
Open article / publication recordDOI: 10.1080/00016340903118000

Gynecologic and Obstetric Investigation
Journal publication
Brief summary: Selected inherited thrombophilia variants were compared between women with repeated IVF failure and controls. The study found no significant association between the tested mutations and implantation failure.
Open article / publication recordDOI: 10.1159/000165776

Journal of Obstetrics and Gynaecology Research
Journal publication
Brief summary: A six-year series reviewed adnexal masses requiring surgery during pregnancy. Most were benign; the results reflect a selected population at a tertiary referral centre.
Open article / publication recordDOI: 10.1111/j.1447-0756.2008.00744.x

Taiwanese Journal of Obstetrics and Gynecology
Journal publication
Brief summary: Single and double IUI were compared in a randomised study of 100 infertile patients. Pregnancy rates did not differ significantly; the authors noted the need for larger studies.
Open article / publication recordDOI: 10.1016/s1028-4559(08)60055-8

BJOG
Journal publication
Brief summary: Outcomes of central incision with Foley catheter placement were reported in 65 patients treated for imperforate hymen. The study evaluates patency of the opening and the surgical approach.
Open article / publication recordDOI: 10.1111/j.1471-0528.2007.01446.x

The European Journal of Contraception & Reproductive Health Care
Journal publication
Brief summary: Efficacy, side effects and reasons for removal were followed in 80 Implanon users. Changes in bleeding patterns were highlighted as an important part of counselling before insertion.
Open article / publication recordDOI: 10.1080/13625180701548040

Geburtshilfe und Frauenheilkunde
Journal publication
Brief summary: Rapid tubal transfer after ICSI was compared with uterine embryo transfer. No improvement was demonstrated; laparoscopy and multiple-pregnancy risks led the authors to question its clinical suitability.
Open article / publication record
Archives of Gynecology and Obstetrics
Journal publication
Brief summary: TNF-alpha, IL-6 and antiphospholipid markers were compared in women with and without recurrent miscarriage. An association with TNF-alpha was reported, without establishing causality or treatment effectiveness.
Open article / publication recordDOI: 10.1007/s00404-003-0547-0

International Urogynecology Journal and Pelvic Floor Dysfunction
Journal publication
Brief summary: A new suspension procedure for stress urinary incontinence and anterior vaginal wall prolapse is described through experience in 31 patients. It aims to support the bladder neck and vaginal wall.
Open article / publication recordDOI: 10.1007/bf01902374

The American Journal of Medicine
Journal publication
Brief summary: This case report concerns the return of normal menstrual cycles after 17 years in a patient with Sheehan’s syndrome. As the index record has no abstract, this description is limited to the subject stated in the title.
Open article / publication recordDOI: 10.1016/0002-9343(87)90480-3

Clinical and Experimental Obstetrics & Gynecology
Journal publication
Brief summary: The study investigated DHEAS, prolactin and testosterone in female infertility and hirsutism. Its historical hormone findings should not be used as current diagnostic thresholds or individual treatment advice.
Open article / publication record
Research Square
Preprint · not presented as a peer-reviewed article
Brief summary: This retrospective preprint compares endometrial co-culture with conventional culture in recurrent implantation failure. It reports favourable embryo-development findings; it is not presented as a peer-reviewed article or proof of causal superiority.
Open article / publication recordDOI: 10.21203/rs.3.rs-3181626/v1
05
Causes, assessments and first steps for women and men.

Explore assessment topics for women and men when pregnancy is taking longer than expected. Learn about preparing for a first consultation, causes of infertility and treatment options.
Prepare for a consultation and plan travel from Konya, Ankara or Karaman.
Women’s health and your journey to parenthood
Explore consultation locations in Konya and Ankara, fertility advice and preparation for travelling from Karaman.

Konya
Consult Prof. Dr. Mehmet Çolakoğlu in Konya for women’s health: private practice location, appointment preparation and initial consultation requests.
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Konya
Request a fertility and IVF consultation with Prof. Dr. Mehmet Çolakoğlu in Konya. Prepare for an initial assessment or a discussion of previous treatment.
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Ankara
Women’s health consultations with Prof. Dr. Mehmet Çolakoğlu at A Life Hospital – Etimesgut, Ankara. Appointment and visit preparation information.
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Ankara
Plan an IVF assessment or second-opinion consultation with Prof. Dr. Mehmet Çolakoğlu at A Life Hospital – Etimesgut in Ankara.
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Karaman
Travelling from Karaman to consult Prof. Dr. Mehmet Çolakoğlu: plan a gynecology appointment in Konya or Ankara and prepare your records.
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Karaman
Explore IVF consultation planning from Karaman: prepare records, travel and follow-up questions for Prof. Dr. Mehmet Çolakoğlu in Konya or Ankara.
Read the guideConsultations are available at the Konya practice and at A Life Hospital – Etimesgut in Ankara.
Contact and directions