Stage of evidence
Early clinical data · Further comparative evaluation underway
Mehmet Çolakoğlu website · Information article ·
How IVM differs
In vitro maturation means collecting immature eggs and maturing them in the laboratory. Moving more of maturation outside the body could reduce medication requirements. This is a research aim, not a promise of injection-free treatment or better success for everyone. [3]
What Fertilo changes
Fertilo uses ovarian support cells derived from stem cells to improve the environment around existing eggs. It does not create a new egg. It should not be interpreted as restoring ovarian reserve or rejuvenating eggs. [1]
What the 2026 study found
A Cell Stem Cell cohort study reported improvements in some maturation and reproductive outcomes compared with traditional IVM. It did not establish superiority over conventional stimulated IVF. The registered FIRST trial is also evaluating the approach. [1] [2]
Questions about suitability
Why is reducing medication important to you? How did you respond to previous stimulation? Could another protocol address the same concern? Ask separately about mature eggs, embryos and live-birth expectations. Reviewing your own reports is more useful than choosing by a technology name alone.
Thinking about timing
Access, research participation and regulatory status vary by country and centre. Ask for a plan covering medication, monitoring, collection and transfer. The possibility of a less demanding future treatment is not, on its own, a reason to delay assessment today.
Frequently asked questions
Does Fertilo make eggs from stem cells?
No. Stem-cell-derived support cells are used to help existing eggs mature outside the body.
Is it more successful than standard IVF?
Adequate comparative evidence has not established that. Findings against traditional IVM do not demonstrate superiority over standard IVF.
Can I reduce my medication myself?
No. Changes to medication or monitoring should be made with your treating clinician.
Scientific sources
Published and updated:
