New steps in science

Robotic ICSI: A New Direction for the IVF Laboratory

Microinjection involves delicate work with very small cells. Automation research explores ways to make these procedures more consistent and reproducible.

An inverted microscope with precision microinjection holders in a reproductive biology laboratory

Stage of evidence

2025 first-live-birth case report · Early clinical stage

Mehmet Çolakoğlu website · Information article ·

What robotic ICSI means

ICSI places one sperm inside an egg. Robotic or digital control aims to automate its micromanipulation steps. It does not mean an entire IVF treatment runs without people: patient care and laboratory supervision still require expertise. [1]

What was reported in 2025?

A case report described the first live birth using a remotely controlled system automating 23 microinjection steps. A birth establishes an important feasibility milestone, not proof of higher success or lower cost in a large comparative trial. [1]

Why it is promising

Standardising precise procedures might improve consistency between laboratories in the future. Whether that translates into better patient outcomes must be measured separately. Technical performance and overall clinical benefit are different questions.

Questions about treatment today

Do not choose treatment solely by a device or robot name. Ask about laboratory quality processes, access to embryology reports and why ICSI is proposed for you. Male-factor findings, previous fertilisation results and the couple's overall assessment should be considered together.

Following the research

Look for comparison groups, patient numbers, live births and safety follow-up in future publications. A single case cannot establish results for everyone. Research can be followed while current assessment and treatment options are planned around individual needs.

Frequently asked questions

Does a robot perform the whole treatment?

No. The research concerns automation of the microinjection part of ICSI.

Has a higher live-birth rate been proved?

The case report cannot establish that. Adequately sized comparative studies are needed.

Is this system offered here?

This article describes research, not a statement that the practice or hospital provides the system.

Scientific sources

  1. Mendizabal-Ruiz et al. · Reproductive BioMedicine Online (2025): remote automated ICSI case report ↗

Published and updated:

Prof. Dr. Mehmet Çolakoğlu

Prof. Dr. Mehmet Çolakoğlu

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Review how semen analysis and previous fertilisation reports may influence your plan with Prof. Dr. Mehmet Çolakoğlu. Request an initial consultation to discuss current options.

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Describing a research approach does not mean it is offered at the practice or hospital. Options appropriate to you are discussed during an individual assessment.

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